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Research Projects


The Radiation Oncology Institute (ROI) strategically funds and advances research where gaps exist about the field of radiation oncology.

  • ROI conducts unbiased research on new and existing treatment outcomes to:
    • Identify linkages between best practices and improved outcomes.
    • Evaluate the efficacy and cost-benefit of radiation therapy
    • Foster multi-institutional research in radiation oncology.

Read ROI's research value statement and ethical standards.

Learn more about our criteria for evaluating potential ROI research initiatives.

Public Health Education and Information Dissemination

  • ROI publishes and disseminates unbiased data and trends about radiation therapy for the public, providers, other medical specialties, payers and other external constituents.
  • ROI serves as a hub and clearinghouse for information and analysis about radiation therapy.
  • ROI supports research that documents the value, safety, benefits and cost-effectiveness of radiation therapy and improves treatment outcomes for patients.
  • ROI envisions the preferred future of the practice and helps the specialty prepare for it.

Research Agenda

To develop a representative view of the most pressing needs for research about the field of radiation oncology, the ROI issued an RFP in the summer of 2010 with the aim of gathering a broad view from many constituent groups in radiation oncology. ROI contracted with the Yale New Haven Health System to conduct the ROI National Radiation Oncology Research Needs Assessment to accomplish this aim. The major topic areas and project ideas that emerged from the assessment (outlined below) form the basis of ROI's research agenda.

The ROI research agenda of projects will vary in size, scope and time frame. The ROI Research Committee will develop and disseminate requests for proposals (RFPs) for each project, evaluate responses and then make their recommendations to the ROI Board of Trustees, which has final approval of researcher selections. For more information on the ROI Research Agenda, please contact Emily Connelly.

Topic Area


Communication (Intervention) Strategies Referring physician decision-making:
identify/develop communication strategies to improve awareness and understanding of radiation therapy.
Safety and Quality Establish general quality indicators for radiation oncology treatment.
Radiation Oncology Registry Develop a radiation oncology registry (and essential components) primarily for comparative effectiveness of treatment outcomes with radiation therapy.
Management of Toxicity in Cancer Survivorship Identify best practices for managing radiation toxicity and other issues in cancer survivorship.
Comparative Effectiveness Research (CER) Conduct comparative effectiveness studies that consider efficacy, toxicity (including QOL) and other outcomes.
Value of Radiation Therapy/Radiation Oncology Assess the value of radiation therapy/radiation oncology relative to other treatment modalities.

View current funding opportunities.